Shows

Moderna Coronavirus Vaccine Test in Monkeys Shows Promise

Monkeys given the Moderna coronavirus vaccine and then deliberately infected were able to fight off the virus, quickly clearing it from their lungs, researchers reported on Tuesday.

The findings do not guarantee that the vaccine will perform the same way in people, but the results are considered encouraging and a milestone in the struggle against the pandemic. If an experimental vaccine fails in monkeys, that is generally seen as a bad sign for its ability to work in humans. This type of study is considered valuable because infecting people on purpose, though sometimes done, is not standard practice.

On Monday clinics around the country began a Phase 3 trial of the vaccine candidate from Moderna, a biotech company based in Massachusetts, with the aim of enrolling 30,000 people to test for safety and effectiveness.

“The virus was cleared very rapidly in the vaccinated animals,” said Dr. Barney S. Graham, the

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C.D.C. Data Shows U.S. Coronavirus Infections Much Higher Than Reported

The number of people infected with the coronavirus in different parts of the United States was anywhere from two to 13 times higher than the reported rates for those regions, according to data released Tuesday by the Centers for Disease Control and Prevention.

The findings suggest that large numbers of people who did not have symptoms or did not seek medical care may have kept the virus circulating in their communities.

The study indicates that even the hardest-hit area in the study — New York City, where nearly one in four people has been exposed to the virus — is nowhere near achieving herd immunity, the level of exposure at which the virus would stop spreading in a particular city or region. Experts believe 60 percent of people in an area would need to have been exposed to the coronavirus to reach herd immunity.

The analysis, based on antibody tests,

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Black Children Are More Likely to Die After Surgery Than White Peers, Study Shows

Black children are more than three times as likely to die within a month of surgery as white children, according to a study published in the journal Pediatrics on Monday.

Disparities in surgical outcomes between Black and white patients have been well established, with researchers attributing some of the difference to higher rates of chronic conditions among Black people. But this study, which looked at data on 172,549 children, highlights the racial disparities in health outcomes even when comparing healthy children.

Researchers found that Black children were 3.4 times as likely to die within a month after surgery and were 1.2 times as likely to develop postoperative complications. The authors performed a retrospective study based on data on children who underwent surgery from 2012 through 2017.

Olubukola Nafiu, the lead author of the study and a pediatric anesthesiologist at Nationwide Children’s Hospital in Columbus, Ohio, said the authors were

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First Coronavirus Vaccine Tested in Humans Shows Early Promise

“It exceeds all expectations,” said Dr. Kizzmekia S. Corbett, a viral immunologist and leader of a team that developed the vaccine at the infectious disease institute.

More than half of the participants had side effects, including fatigue, chills, headaches, muscle aches and pain at the injection site. Some had fever. One person who received the low dose developed hives and was withdrawn from the study. None of the side effects were considered serious.

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