Vaccine

Health Experts to F.D.A.: Make Your Vaccine Deliberations Public

A coalition of leading public health experts urged the Food and Drug Administration on Wednesday night to conduct full safety and efficacy reviews of potential coronavirus vaccines before making the products widely available to the public.

In a letter signed by nearly 400 experts in infectious diseases, vaccines and other medical specialties, the group called on Dr. Stephen Hahn, the F.D.A. commissioner, to be forthcoming about the agency’s deliberations over whether to approve any new vaccine, in order to gain the public’s trust.

“We must be able to explain to the public what we know and what we don’t know about these vaccines,” noted the letter, which was organized by the nonprofit Center for Science in the Public Interest. “For that to happen, we must be able to witness a transparent and rigorous F.D.A. approval process that is devoid of political considerations.”

More than 30 experimental coronavirus vaccines are in

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Novavax’s New Covid-19 Vaccine Studies Praised By Scientists

Novavax, the little-known Maryland company that received a $1.6 billion deal from the federal government for its experimental coronavirus vaccine, announced encouraging results in two preliminary studies on Tuesday.

In one study, 56 volunteers produced a high level of antibodies against the virus without any dangerous side effects. In the other, researchers found that the vaccine strongly protected monkeys from coronavirus infections.

Although it’s not possible to directly compare the data from clinical trials of different coronavirus vaccines, John Moore, a virologist at Weill Cornell Medicine who was not involved in the studies, said the Novavax results were the most impressive he had seen so far.

“This is the first one I’m looking at and saying, ‘Yeah, I’d take that,’” Dr. Moore said.

Angela Rasmussen, a virologist at Columbia University who was not involved in the studies, called them “encouraging preliminary results,” but cautioned that it won’t be possible to

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Johnson & Johnson’s Covid-19 Vaccine Protects Monkeys, Study Finds

An experimental coronavirus vaccine developed by Johnson & Johnson protected monkeys from infection in a new study. It is the second vaccine candidate to show promising results in monkeys this week.

The company recently began a clinical trial in Europe and the United States to test its vaccine in people. It is one of more than 30 human trials for coronavirus vaccines underway across the world. But until these trials are complete — which will probably take several months — the monkey data offers the best clues to whether the vaccines will work.

“This week has been good — now we have two vaccines that work in monkeys,” said Angela Rasmussen, a virologist at Columbia University who was not involved in the studies. “It’s nice to be upbeat for a change.”

But she cautioned that the new results shouldn’t be used to rush large-scale trials in humans. “We just can’t

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Moderna Coronavirus Vaccine Test in Monkeys Shows Promise

Monkeys given the Moderna coronavirus vaccine and then deliberately infected were able to fight off the virus, quickly clearing it from their lungs, researchers reported on Tuesday.

The findings do not guarantee that the vaccine will perform the same way in people, but the results are considered encouraging and a milestone in the struggle against the pandemic. If an experimental vaccine fails in monkeys, that is generally seen as a bad sign for its ability to work in humans. This type of study is considered valuable because infecting people on purpose, though sometimes done, is not standard practice.

On Monday clinics around the country began a Phase 3 trial of the vaccine candidate from Moderna, a biotech company based in Massachusetts, with the aim of enrolling 30,000 people to test for safety and effectiveness.

“The virus was cleared very rapidly in the vaccinated animals,” said Dr. Barney S. Graham, the

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